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Santonin - Structural elucidation & Synthesis #mscchemistrynotes #notes ‪@itschemistrytime‬
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Structure elucidation of santonin
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SOLVED: 7. The triterpene costunolide can be synthesized in seven steps from the natural product santonin; a naturally occurring antiparasitic The reason it is used is to provide critical chiral centers that are difficult to synthesize otherwise:Using the structures of the starting material and product; and a list of reagents/conditions; plan a synthesis of the product:hv; 0'C1. Brz, AcOH 2. LiCOz, LiBr; DMF Hsteps1. LAH 2. TsCl; pyr 3. KOtBuHz, Pdlcsantonincostunolide
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