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  1. JCI - Welcome

    6 days ago · In this issue of the JCI, Goala et al. uncovered a mechanistic link between IFN-γ–driven inflammation and disrupted neutrophil homeostasis, revealing that cytokine release syndrome (CRS) …

  2. JCI - About the Journal of Clinical Investigation

    You may submit manuscripts for consideration solely by the JCI or select the Dual-Journal Submission option to have your manuscript evaluated by the JCI and JCI Insight. Start your submission by …

  3. JCI - Welcome

    View Volume:136 - 2026135 - 2025134 - 2024133 - 2023132 - 2022131 - 2021130 - 2020129 - 2019128 - 2018127 - 2017126 - 2016125 - 2015124 - 2014123 - 2013122 - 2012121 ...

  4. JCI - Volume 135, Issue 24

    Dec 15, 2025 · In this issue of the JCI, Miao et al. demonstrated that MCC tumor survival requires neuroendocrine-lineage transcription factors, which are recruited to superenhancers (SEs) with the …

  5. JCI - Author Information Center

    JCI is a Gold Open Access journal and deposits all published research articles in PubMed Central, which satisfies the NIH Public Access Policy and other similar funding agency requirements.

  6. JCI - Inducible CCR2+ nonclassical monocytes mediate the regression …

    Nov 15, 2024 · Kurihara C, et al. Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment. JCI Insight. …

  7. JCI - Submission instructions - first

    Submit a manuscript directly to the JCI through your account on the JCI’s submission website. Follow the instructions to either register for an account or access your existing account.

  8. JCI - Endothelial MICU1 protects against vascular inflammation and ...

    JCI Insight. 2022;7 (4):e154447. View this article via: JCI Insight PubMed Google Scholar Singh R, et al. Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in …

  9. JCI - Deep immunophenotyping reveals circulating activated …

    Mar 17, 2025 · JCI Insight. 2016;1 (17):e90045. View this article via: JCI Insight CrossRef PubMed Google Scholar Mankia K, et al. EULAR points to consider for conducting clinical trials and …

  10. JCI Insight - Author Information Center

    JCI Insight and the American Society for Clinical Investigation (ASCI) are dedicated to upholding the highest standards of integrity and ethical conduct in research, and in its evaluation and related …