This Collection seeks to shape our field’s understanding of cardiac regeneration today with a broad scope of research and translational studies to inspire ongoing efforts to create novel treatments ...

The field of cancer research is increasingly exploring the intricate intersections among epigenetics, cancer metabolism, and immunotherapy. These ...

Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but this isn’t the case in adults. After a heart attack, most adults struggle to ...

Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but adults aren't so lucky. After a heart attack, most adults struggle to regenerate ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

Study in experimental animals reveals fundamental differences in how immune system drives healing based on age Newborn immune systems see, then eat dying cells, triggering production of bioactive ...

Around the globe, heart disease remains one of the top causes of death. Once patients begin to suffer from serious heart problems, like heart attacks and heart failure, the heart muscles become ...

While these animals retain the regenerative ability throughout adulthood, most mammals, including mice and humans, lose this capacity shortly after birth. 4 Scientists are interested in determining ...

Northwestern Medicine researchers are looking at how newborns' newly developed immune systems can regenerate cardiac tissue. They say understanding the mechanism in infants could lead to tissue repair ...

In recent years, the complex ecosystem surrounding cancer cells, known as the tumor microenvironment (TME), has become a ...