Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, microenvironmental stress, and therapeutic pressure. This article explains how dietary ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Researchers at National Taiwan University have developed a modular platform to reprogram tumor-derived extracellular vesicles ...

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich conditions, producing massive amounts of lactate that accumulate in the tumor ...

Cancer represents a key challenge in medical science, manifesting as a disease where the immune system fails to recognize and eliminate tumor cells. The phenomenon of immune evasion by cancer cells ...

A new study led by researchers at Huntsman Cancer Institute at the University of Utah (the U) shows that regular exercise may do more than help colon cancer patients feel better—it may actually change ...

Lewis Zhichang Shi, M.D., Ph.D., professor in the Department of Radiation Oncology, has been named the latest recipient of the school’s Featured Discovery award. This recognition celebrates notable ...

Scientists have discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth. The lab of Filippo ...

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...