ascopubs.org

Sensitization of prostate cancer cells to TRAIL-induced apoptosis by CDDP: Involvement of NF-κB, YY1 and RKIP in upregulation of DR5 expression

A pilot study of safety and efficacy of pandimex with or without paclitaxel in the treatment of advanced solid tumors No significant financial relationships to disclose. This is an ASCO Meeting ...
ascopubs.org

A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer

HGS-ETR2—A fully human monoclonal antibody to TRAIL-R2: Results of a phase I trial in patients with advanced solid tumors This is an ASCO Meeting Abstract from the 2006 ASCO Annual Meeting. This ...
The Scientist

Drug Makers on the Apoptotic Trail

Not surprisingly, many major pharmaceutical companies recognize the value of apoptosis research. Understanding and controlling programmed cell death is expected to yield new drug discoveries and ...