Researchers have developed 'tomoseqr' -- a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free to use and has been ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

A series of announcements in recent weeks shows just how much the spatial biology field has matured in the years since Nature Methods recognized spatial biology—which it called spatially resolved ...

Breakthrough research details how distinct tissue niches and cell communication contribute to chronic active lesions in MS. Study: Cell type mapping reveals tissue niches and interactions in ...

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...

Understanding the composition and architecture of cells within tissues is fundamental to studying tissue function and more broadly, human biology. The complex dynamics of cellular functions and ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper ...