George: The phase 1/2 study is evaluating a new compound called DCC-3009. It is a drug that was designed specifically to work ...

Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...

GISTs originate from interstitial cells of Cajal and are staged by size, location, mitotic rate, and genetic mutations, influencing treatment strategies. Diagnosis involves imaging, endoscopy, biopsy, ...

Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be useful in assessing these tumors' potential to spread, and may even be targets for future prostate ...

Development of an artificial intelligence-based diagnostic system for the detection of abnormal colposcopic findings. A comparative study of the effectiveness of multiagent platinum based concurrent ...

Gastrointestinal stromal tumors (GISTs) are growths that form in the digestive tract. The overall GIST survival rate for 5 years is 85%. However, this rate cannot predict the survival of any ...

GIST stands for gastrointestinal stromal tumor. When tumors spread from the gastrointestinal (GI) tract to distant tissues or organs, it is called a metastatic GIST. Newer therapies, such as imatinib ...

The investigation of multiple molecular targets with next-generation sequencing (NGS) has entered clinical practice in oncology, yielding to a paradigm shift from the histology-centric approach to the ...

Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease.

Seminomas and nonseminomas make up most cases of testicular cancer, but there are other rare types. The differences between types can affect how quickly they spread and how doctors treat them.