RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Carcinoma of prostate sequencing of tumor and clinical endpoints (CAPSTONE): Clinical implications of recurrent genomic alterations in lethal prostate cancer.

The discipline of bioinformatics integrates biology and computer science to improve our understanding of complex biological systems. Bioinformatic analysis describes the processing of biological data ...

Nanopore sequencing offers comparable accuracy to short-read NGS for IGH clonotyping in CLL, with advantages in cost and laboratory footprint. The study confirms reliable somatic hypermutation status ...

Even the most straightforward next-generation sequencing (NGS) experiments can be expensive and time-consuming. Thus, it’s a good idea to test your workflow on a few samples to make sure you’ll get ...