Phototherapy (PT) has emerged as a promising non-invasive strategy for treating tumors. Characterized by its minimally invasive nature, PT uses non-ionizing radiation, making it suitable for tumors ...
Developing targeted small molecule quantitative workflows for clinical research presents many challenges to researchers. From determining the optimum methods needed to enhance selectivity and ...
Antibody-drug conjugates (ADCs) are a growing class of biotherapeutics that have transformed targeted therapy, especially in oncology. By making use of monoclonal antibodies’ specificity to deliver ...
In an interview with Targeted Oncology, Sarbajit Mukherjee, MD, gastrointestinal (GI) medical oncologist at Baptist Health ...
Scientists at Shanghai Tech University have used the scaffold-hopping artificial intelligence model Geminimol to identify N-methyl-D-aspartate (NMDA) receptor ligands that show selectivity and ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how structure-guided design of picomolar-level macrocyclic TRPC5 channel inhibitors with antidepressant activity.