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RNA-seq outperforms DNA methods in detecting actionable cancer mutations

In the study, "Clinical utility of targeted RNA sequencing in cancer molecular diagnostics," published in Nature Medicine, researchers implemented a targeted RNA-seq assay to evaluate 2,310 tumors ...
Science Daily

Mysterious RNA led scientists to a hidden layer of cancer

A mysterious RNA found in breast cancer led scientists to uncover an entire hidden class of cancer-specific RNAs across ...
Medical Xpress

Deep-learning algorithms enhance mutation detection in cancer and RNA sequencing

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic ...
GEN

Microbial RNA Modifications Predict Colorectal Cancer in Liquid Biopsy

University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...
ascopubs.org

Pan-cancer gene set discovery via scRNA-seq for optimal deep learning based downstream tasks.

Human vs. AI: A comparative effectiveness study of large language models for automated biomarker extraction. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does ...
GEN

Direct RNA Sequencing Supports Novel Discoveries in RNA Biology

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...