Long-term outcomes of neoadjuvant chemotherapy (NAC) before bladder-sparing chemoradiotherapy (CRT) for patients with nonmetastatic muscle-invasive bladder cancer (MIBC). This is an ASCO Meeting ...
The onset and aggressiveness of cancer are related to the abnormal behavior of certain genes, known as oncogenes. The best-known of these alterations is mutation, but it is not the only one. Sometimes ...
Proto-oncogene Vav (VAV1) is a guanine exchange factor that is crucial for T- and B-cell receptor signaling. Assays in Vav1-knockout murine models had previously demonstrated diminished effector ...
In cellular and animal models of neuroblastoma, small cell lung cancer and colon cancer, this strategy reduces tumours, prolongs survival and triggers a tumour-fighting immune response. The study, ...
The MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it difficult to treat various human cancers. When MYCN is overactive, ...
A new study from researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) sheds light on why certain oligodendrocyte progenitor cells (OPCs) in the adult brain ...
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