In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, ...

Genetic diseases that result from truncated proteins can be targeted by so-called nonsense suppression therapies—drugs that prevent protein translation from terminating prematurely. A new ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival. Bacteria are no exception, with molecular machines involved in ...

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival. Bacteria are no exception, with molecular machines involved in ...

Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...