A new Brazilian study has revealed the key role of the protein periostin and stellate pancreatic cells in allowing pancreatic ...

Brazilian research shows that stellate pancreatic cells produce periostin, remodeling tissue and facilitating tumor infiltration, a key mechanism of the aggressiveness and high mortality of the ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an estrogen independent manner. Targeting vimentin and/or the long ...

“In some cancers, brown adipose tissue becomes pathologically overactive and causes uncontrolled metabolic energy expenditure, leading to cachexia,” Villarroya said. “In this case, the function of the ...

Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could label proteins in millions of cells. Conventional protein-tagging methods, ...

Two new research papers from the Living Brain Project at Mount Sinai present what is, by several metrics, the largest investigation ever performed of the biology of the living human brain. The papers ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

Much of pancreatic cancer’s evasive and deadly nature may come down to low levels of one gene. In A Nutshell Early detection, ...

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility. Using the ...