Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their ...

Macromolecular crowding is a central concept in understanding how proteins function in the dense and heterogeneous intracellular environment. In crowded cellular conditions, high concentrations of ...

For decades, scientists assumed that order drives efficiency. Yet in the bustling machinery of mitochondria—the organelles ...

A novel protein cage system can control and visualize orientational changes in aromatic side chains upon ligand binding. By inducing coordinated molecular changes, this approach enables precise ...

A team of international researchers led by scientists at City of Hope ®, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National ...

The cell cytoskeleton is modulated by motor proteins, known as dyneins, that generate force and movement on microtubules to control a wealth of biological processes, including motility, cell division, ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Protein folding helpers such as TRiC and prefoldin (PFD) are crucial for the correct folding of many essential proteins. In a Nature study, researchers from the Max Planck Institute of Biochemistry ...