Primordial germ cells, which emerge around day 16 in early human embryos, develop to form oogonia so that eventually, the number of oocytes that are present in an adult female is fixed at birth. After ...

Oocytes are among the longest-lived cells. Scientists have been trying to understand what enables such longevity, because oocytes—like other nondividing, long-lasting cells—have a high risk of ...

How do immature egg cells maintain genetic quality for decades before they mature? Scientists find unusual safeguards in this quiescent cell that may inform research into fertility. Out of all the ...

Fukuoka, Japan—Researchers have uncovered both the mathematical and biological mechanism behind the rugged structures at cell boundaries found in tissues such as the kidneys and nasal glands. The team ...