A new collaborative study shows how blood vessel genes play a critical role in motor neuron development by telling blood vessels to get out of the way. The discovery has implications for understanding ...

Effective axon regeneration is critical for restoring nerve function in patients with axon injury-related neurological diseases, yet adult mammals show limited regenerative capacity in central axonal ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS). The study, ...

A progenitor-derived corticospinal-like neuron in cell culture, extending its long axon, even in isolation. The cell body (or "soma"; immunolabeled by Tuj1 antibody in red) is at the top, with the ...

To allow for the local translation of proteins that suit the ever-changing needs of the axon, neurons must ship transcripts from the soma to their outermost reaches. For thousands of these mRNAs, ...