Genetic prediction of common diseases is based on testing multiple genetic variants with weak effect sizes. Standard logistic regression and Cox Proportional Hazard models that assess the combined ...

The rationale for multiplicative models in the context of MTMM covariance matrices, as developed by Swain and Browne, is described and illustrated with several sets of empirical data. Comparisons with ...

Reduced rank approximation of matrices by Householder-Young methods is shown to be equivalent to fitting of a bilinear (multiplicative) model and to projection onto an optimally chosen subspace. The ...

Clinical utility of expanded screening of the KRAS and NRAS genes for Metastatic Colorectal Cancer: Evaluation of the CRC RAScan tumor test as a companion diagnostic to determine efficacy of anti-EGFR ...