Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesineConvergence of impaired ...

Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an ...

Autism and Alzheimer’s disease have long occupied separate corners of neuroscience. One is diagnosed in childhood; the other emerges late in life. But a convergence of epidemiological data, genetic ...

Alzheimer's disease (AD) is a highly debilitating neurodegenerative disease characterized by the progressive loss of memory and decline of mental functions. Earlier research has uncovered some of the ...

Add Yahoo as a preferred source to see more of our stories on Google. Microglial receptor ADGRG1 helps immune cells eat amyloid plaques and may offer new hope for Alzheimer's treatment. (CREDIT: ...

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering human ...

(Left) Correction of pathogenic Csf1r mutation by Mr BMT effectively rescues pathological changes in the brain, motor impairment and cognitive decline in ALSP mice. (Right) tBMT-mediated microglia ...

Microglia respond to proteinopathies by changing their shapes and expression profiles in different ways. Here’s one that has been somewhat overlooked: rod-shaped microglia. These long, straight cells ...

In tauopathies, scientists tend to focus on neuronal tau. They track its pathology and blame it for dysfunctional microglia. Now, researchers led by Celeste Karch at Washington University, St. Louis, ...

In a recent study published in the journal Neuron, researchers at the University of Cambridge and Newcastle University, UK, examined the relationship between autophagy, aging, and neurodegeneration.