Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...

A graphic of a purple and magenta Cas9 protein, which is a somewhat round, but uneven, ball, bound to a yellow and orange ...

A machine learning model analyzing CpG-based DNA methylation accurately predicted the origin of many different cancer types ...

Most gene-editing tools are blind to context. Point them at a DNA sequence and they cut, whether that sequence sits inside a ...

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

Women With Synchronous Primary Cancers of the Endometrium and Ovary: Do They Have Lynch Syndrome? Currently, no validated blood-based assays accurately predict treatment response or outcome in ...

From the unveiling of a cloud-based computational platform for metabolomics data analysis, to demonstrating the efficacy and safety of therapeutic antibodies using an innovative mouse model, here are ...

The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...

Myelodysplastic syndromes (MDS) are malignant disorders arising from hematopoietic stem cells, yet the precise epigenetic abnormalities occurring in the primitive stem cells remain poorly understood.