Longitudinal calcium imaging in the medial prefrontal cortex reveals the emergence of de novo task representations and reward-associated replay.

Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...

"If the human brain were so simple that we could understand it, we would be so simple that we couldn't." — Emerson M. Pugh.

Many horse owners think the existence of the prefrontal cortex is a major controversy in equine science. It’s not. It’s just an area that’s riddled with misinformation. Curiously, most people—horsey ...

Understanding how the brain learns and applies rules is the key to unraveling the neural basis of flexible behavior. A new study from the University of Toyama, Japan, reveals that our ability to ...