T-cell profiles derived from blood and renal biopsy may be novel biomarkers of lupus nephritis treatment response, study findings suggest.

Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells ...

Lupus nephritis is a serious complication of lupus — and because it doesn’t always cause symptoms right away, it’s important to find it early. Talk to your lupus doctor about getting screened (tested) ...

A common gut bacterium may be implicated in lupus kidney disease, and could potentially alter the diagnosis and treatment of ...

Lupus nephritis is a serious complication of lupus that is caused by inflammation of the kidneys. It affects up to 60% of people with lupus and usually occurs within 5 years of diagnosis. If left ...

Lupkynis is a medicine that is used for a specific kidney disease called lupus nephritis. Lupus nephritis is a kidney condition that affects people with systemic lupus erythematosus (SLE). SLE is an ...

The addition of obinutuzumab to standard care increased the complete renal response rate by 13.4 percentage points in patients with active proliferative lupus nephritis. At week 76, a significantly ...

Scientists have linked overgrowth of a gut bacterium to lupus nephritis flares, identifying a toxin that may damage kidneys and a blood-test biomarker for early detection. The findings suggest a ...

A regulatory decision is expected by October 2025. The Food and Drug Administration (FDA) has accepted the supplemental Biologics License Application (sBLA) for obinutuzumab (Gazyva ®) for the ...

Weight-based dosing misses accounting for factors such as chronic kidney disease or chronic transaminitis, which could ...

The body's immune reaction to increased levels of a toxic molecule, that is part of the structural coat of a bacterial species in the human gut, may serve as a marker of who is most at risk of ...

The trial met its primary endpoint showing a significant improvement in complete renal response with obinutuzumab with standard therapy vs standard therapy alone after 76 weeks. Positive topline ...