Lipid A, the endotoxic component of lipopolysaccharide (LPS), is fundamental to the architecture and function of Gram-negative bacterial outer membranes. It not only anchors LPS to the cell surface ...

From vaccines to personalized cancer therapies, scientists are studying the use of mRNA across many clinical applications. However, there are several factors that are unique to mRNA drug product ...

Lipid research investigates the structure, function and metabolism of fats, covering their roles in industrial processes, the environment and health. Emerging research areas include nutrient ...

A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...

Researchers at Entos Pharmaceuticals report today in Cell that they have developed a particle that can deliver DNA and RNA to many tissues without triggering an immune response (2024, DOI: ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...