The decreased transport of kinesin-I and potential cargoes in APP-null sciatic nerves suggested that APP would be abundant relative to kinesin-I. Quantitative western blots with protein standards ...
Kinesins conventionally act as molecular motor proteins that translocate along microtubules. However, several kinesins also control microtubule polymerization dynamics. New work shows that the yeast ...
Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...
D. Betterton (2009). Biophysical Journal96, 3050. arXiv:0812.3908. Download. Proteins from the kinesin-8 family promote microtubule (MT) depolymerization, a process thought to be important for the ...
Boundless Bio's first direct ecDNA-targeting asset, is entering clinical trials with promising preclinical efficacy. Check ...
The structure of a key part of the machinery that allows cells to divide has been identified by researchers, opening new possibilities for throwing a wrench in the machine and blocking runaway cell ...
Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks. This miniature highway system is vital for keeping neurons healthy: ...
Learn more about an important cellular protein called kinesin from this video by the University of California San Francisco (UCSF), and Ron Vale Ph.D., a UCSF researcher. Kinesin is a motor protein, ...
Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?
Boundless Bio (Nasdaq: BOLD), a clinical-stage oncology company interrogating extrachromosomal DNA (ecDNA) biology to deliver ...
Boundless Bio (Nasdaq: BOLD), a clinical-stage oncology company interrogating extrachromosomal DNA (ecDNA) biology to deliver ...
The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in ...