Myelodysplastic syndromes (MDS) often require frequent blood transfusions for anemia, which can lead to iron overload. Over time, extra iron can damage organs throughout the body. Underlying MDS ...

Starting iron chelation therapy early may prevent growth problems and organ damage from iron overload in children with TDT. Currently approved medications have limitations for use in very young ...

Clarence Moore, PharmD, BCPS, BCOP, assistant professor at Shenandoah University in Ashburn, Virginia, discussed the potential complications for patients with beta thalassemia associated with iron ...

—Researchers recently examined how different iron chelation medications—deferoxamine, deferiprone, and deferasirox—impacted iron stores and long-term health in patients with transfusion-dependent ...

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia. Patients with ...

Saturation of TfR1 leads to the dissociation of Hfe and the binding of the alter to the TfR2, which in turn influences the binding of BMP6 to its receptors on the membrane. Increased liver iron ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Having too much of a heavy metal—found in some foods, medications, and supplements—in your body can cause toxicity or poisoning. A healthcare provider may prescribe a heavy metal detox, such as ...

Please provide your email address to receive an email when new articles are posted on . The FDA approved deferiprone for treatment of children or adults with transfusional iron overload due to sickle ...

New evidence suggests that trapping iron in unusable forms may starve vulnerable neurons, challenging decades of thinking about iron toxicity in Parkinson’s disease and opening new therapeutic ...