Saphnelo, a human monoclonal antibody, is a type 1 interferon (INF) receptor antagonist that inhibits a key protein in the immune system called the IFNAR receptor. This protein acts like a transmitter ...

Researchers from Mount Sinai have uncovered a possible explanation for why a flu infection can lead to heart disease. They’ve shown from work with mouse models and human data how the immune system ...

Assembly Bio leadership team will be joined by Professor Edward J. Gane, MBCHB, MD, FRACP, MNZM , an internationally-recognized hepatologist, and authority and investigator in hepatitis clinical ...

LONDON, United Kingdom — After years of clinical trial failures, an anti-interferon antibody, anifrolumab, has been shown to dramatically reduce disease activity in extrarenal systemic lupus ...

Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There ...

A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell ...

Giulia Pasquesi in the lab at the University of Colorado Boulder. For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers.

Novel TROP2-targeted CAR T cells with high specificity and sustained efficacy for solid tumors in animal models. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract ...