Heart failure has increasingly been recognized as a complex, metabolism-driven syndrome that extends far beyond traditional models of hemodynamic ...

Reconstruction of amino acid metabolism in breast cancer (BC). Amino acid metabolism in BC has been extensively studied, with a focus on the role of various regulatory genes. The integration of ...

Specialized metabolites form a cornerstone of plant defensive and adaptive strategies, particularly in response to abiotic stress. Recent research has ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Plants are a rich and renewable source of compounds used in medicines, food ingredients, and cosmetics. Since growing an entire plant just to extract a few specific compounds is rather inefficient, ...

From cancer-fighting Taxol to fragrant rose oils, plant terpenoids shape our world in surprising ways. Scientists are now ...

Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate.

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

A metabolic enzyme found in the support cells surrounding tumors may hold the key to predicting which cancer patients will ...

New study shows how bacteria juggle energy needs while digesting complex carbons. For years, scientists have marveled at bacteria’s ability to digest the seemingly indigestible, including carbon from ...