The analytical workflow begins with the separation of the complex protein mixture, often utilizing liquid chromatography (LC) or capillary electrophoresis (CE) coupled directly to the MS system.

Chemical analysis is a critical need in our high-tech industrial world. Mass spectrometry, with its high sensitivity and high selectivity, occupies a pivotal role in the detection and quantitation of ...

New Intact Mass software application on waters_connect enables simplified and significantly faster analysis of biomolecules for mass and purity Intact Mass App is now available as an upgrade for new ...

New Workflows Have Been Developed to Examine the Heterogeneity of mAb Products Recombinant monoclonal antibodies (mAbs) have been among the most successful pharmaceutical products. Global sales for ...

This article and associated images are based on a poster originally authored by William LaMarr, Dave Garby, Jeremiah Bowers, Lisa Boatner, Somayeh Talebzadeh, Aaron Wolfe, Sekar Ramachandran, and ...

Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...

Researchers have detailed PEPPI-MS, an experimental protocol combining high-resolution protein fractionation using SDS-polyacrylamide gel electrophoresis (SDS-PAGE) with the latest mass spectrometry ...