Arrowhead Pharmaceuticals has reported early-phase data on a pair of gene silencing drug candidates in obesity, posting ...

Arrowhead Pharmaceuticals said Tuesday that its gene-silencing candidates helped people with obesity lose fat.

Revolutions in gene therapy are rapidly changing the landscape of modern medicine. Revolutions in gene therapy are rapidly changing the landscape of modern medicine, forcing society and science alike ...

The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...

In a recent study published in the journal Nature, scientists used mouse models to test whether in vivo gene silencing is sustained after transient delivery and expression of engineered ...

RNAi: Five Tips to Better Silencing - Table 1: siRNA Construction KitsCompanyKitsiRNAs per kit (or yield in mg RNA/ml)Price (USD)Ambionwww.ambion.comMEGAscript RNAi Kit20$285Silencer siRNAConstruction ...

Aristides Tagalakis does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations ...

Researchers describe a novel form of gene regulation that is altered in bladder cancer, leading to the boosting of a gene pathway that helps the cancer cells survive during rapid growth. The work ...