Laminins are heterotrimeric glycoproteins that form a fundamental scaffold within the extracellular matrix, particularly in basement membranes. Each laminin molecule comprises α, β and γ chains ...

Peptide-based signaling systems continue to occupy a central role in modern biochemical inquiry, particularly in areas concerned with extracellular matrix (ECM) dynamics and structural protein ...

In a recent study, led by corresponding author, Anna-Maria Liphardt, PhD, of the Rheumatology and Immunology Department at Friedrich-Alexander-Universität Erlangen-Nürnberg and the ...

Aging-related cognitive decline is an early symptom of Alzheimer's disease and other dementias, and on its own can have substantial consequences on an individual's ability to perform important ...

Estrogen loss in aging females causes the collapse of the brain's extracellular matrix, increasing Alzheimer's risk.

New research from the University of Eastern Finland sheds light on the mechanisms associating obesity with inflammation by exploring tiny membrane particles, known as extracellular vesicles, secreted ...

This is the first study of its kind to examine this part of the brain and its link to estrogen.

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study ...

New research from Northwestern Medicine reveals how post-menopausal hormone shifts can weaken the brain’s memory networks.