Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Embryonic germ layers are the fundamental organizing principle in animal development. They provide the structural basis from which tissues and organs arise. During early embryogenesis, cells divide to ...

In the course of early embryonic development, pluripotent stem cells first give rise to three lineages or ‘germ layers’, which then generate all cell types, tissues and organs of the human body, e.g.

Fredrik Lanner is in the Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Division of Gynecology and Reproduction, Karolinska University Hospital, Stockholm, and ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilized egg, starts to develop, ...

Huntington’s disease (HD) was the first neurological disorder to be linked to a mutation in a single gene—a discovery made more than 25 years ago. However, neither the pathogenic mechanisms leading to ...

In an interview with Torbjörn Ogéus, Stockholms led- & smärtklinik (SLS), Open Access Government explores how the landscape of regenerative medicine is shifting ...