A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development. The research, led by scientists at the ...

In humans, a specialized mRNA translation circuit predetermines the competence for heart formation at an early stage of embryonic development, a research team at the Center for Molecular Medicine ...

The epicardium is the mesothelial cell sheet covering the heart’s outer surface. Long considered a simple barrier between the pericardial cavity and the myocardium, it is now recognized to hold key ...

Scientists at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences have developed a multi-chamber organoid that mirrors the heart’s intricate structure. The human ...

Cardiogenic growth factors play important roles in heart development. Placental growth factor (PLGF) has previously been reported to have angiogenic effects; however, its potential role in ...

Infants born with Down syndrome, the genetic condition caused by an extra copy of chromosome 21, or trisomy 21, are highly predisposed to congenital heart defects. It is estimated that nearly half of ...

The findings shed light on the origins of congenital heart defects and could open new avenues in regenerative medicine and tissue bioengineering. A study published today in the journal Developmental ...

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists -- so far. A new multi-chamber ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

An international team of experts in embryology and bioethics has published the first white paper on the use of embryonic ...