Decades ago, researchers showed that Down syndrome (also known as trisomy 21), was caused when individuals carried an extra copy of chromosome 21. Down syndrome is also the most common genetic cause ...

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least in lab-grown human cells. Down syndrome occurs when a person is born with ...

Last month, San Diego-based biotech company Sequenom released its long-awaited early pregnancy test for Down syndrome. Unlike previous methods such as amniocentesis, which carries a significant risk ...

After decades of mystery, researchers at Gladstone Institutes identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. SAN FRANCISCO—October 22, ...

The genetic cause for the most common type of hearing loss in children with Down syndrome has been identified in mice by researchers at UCL, the Francis Crick Institute and MRC Harwell Institute. Down ...

The first strides have been made in trying to better understand Down syndrome, along with the hopes of finding ways to help those born with it. Down syndrome, also referred to as trisomy 21, is caused ...

Researchers have identified a key gene that drives susceptibility to ‘glue ear’ in people with Down syndrome, paving the way for future targeted therapies. The work, published today as a Reviewed ...

For children with Down syndrome (DS) or other genetic syndromes (OS), adenotonsillectomy seems to be safe, with a low rate of complications, according to a study published online Oct. 31 in the Ear, ...

In the peri-urban sprawl of Githurai, Kiambu County, Oliver Njenga's home is filled with the joyful laughter of his two-year-old daughter, Alma. She runs across the floor with boundless energy, a ...

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life. For decades, scientists have ...