Cytokines such as interleukin-2 have long held great promise as cancer treatments, but they can cause nasty side effects that have limited their use. They’re not very good drugs because they haven’t ...

Cytokines are key to immune regulation. Their extensive impact on human biology and disease has led to their long-term therapeutic use in treating cancer and a range of other diseases. Interleukin-2 ...

Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...

Cancer immunotherapy has advanced significantly in recent years, dramatically improving patient prognosis and survival. The majority of cancer immunotherapy research currently focuses on the first T ...

Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...

When people become gravely ill from COVID-19, a cytokine storm — their body’s own reaction to the virus — may sometimes make things worse. The phenomenon has been described as “an immune system gone ...

People often get immunotherapy as a treatment for cancer. These immunotherapy treatments can be effective, but they may cause your immune system to have an unnatural response. Your body, as a result ...

Researchers have developed a new method of locally delivering cytokines alongside T cells that could lead to improved CAR-T cell therapies. CAR-T cell therapies utilize engineered T cells that have a ...

Researchers at Virginia Polytechnic Institute and State University have developed a new approach to harnessing immunostimulatory cytokine proteins as a potential immunotherapy. Unlike previous methods ...