Introduction Patients with SLE have an increased risk of infections and infection-related mortality, which may be associated ...
Clonally expanded CD8+ T cells are key drivers of alopecia areata, mediating epithelial cell death and immune infiltration. JAK inhibitors are approved for AA treatment, but recurrence is common, ...
引言很多人谈到抗肿瘤免疫，第一反应是“杀伤”：CD8+T细胞、自然杀伤细胞(NK cells)、CAR-T细胞，像精准武器一样识别癌细胞，然后将其清除。6月18日，《Science》的研究报道“CD4+ T cells impair tumor growth through IL-3 and TNF-dependent vascular damage”提醒我们：免疫系统还有另一种更隐蔽、更依赖组织 ...
A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...
The identification of CD8+ TIGR cells yields new insights into organ-specific immune regulation and potential therapeutics for inflammatory bowel disease.
Efficacy and Safety of Sacituzumab Govitecan in Patients With Advanced Solid Tumors (TROPiCS-03): Analysis in Patients With Advanced Endometrial Cancer The authors report on a prognostic tool (CD3 ...
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells. CD8 + T ...
Cause-Specific Mortality in a Cohort of 1,435 Patients With Hodgkin Lymphoma Treated Between 1985 and 2014: A Nationwide Chilean Cohort Study Healthy volunteers were recruited and underwent ...
A study has revealed how the Epstein-Barr virus triggers T-cell responses that may drive autoimmunity in MS patients.
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