Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated ...

Mutations in homologous recombination DNA damage repair genes and treatment outcomes to immune checkpoint inhibitors in melanomas. Recombinant human adenovirus type 5 (H101) combined with anti-PD-1 ...

Zoledronic acid is a potent, new-generation bisphosphonate indicated for the treatment of documented bone metastasis in patients with solid tumors and bone lesions associated with multiple myeloma.

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

Former President Joe Biden was diagnosed with an “aggressive form” of prostate cancer that has a five-year survival rate of between 30% and 40%. The former president’s prostate cancer is characterized ...

Bone imaging plays a pivotal role in the diagnosis, treatment planning and follow‐up of patients with cancer metastasis. Advances in hybrid imaging modalities, particularly single-photon emission ...

Results suggest bone-protecting agents should be used in patients with metastatic castration-resistant prostate cancer and bone metastasis, especially in the era of androgen receptor pathway ...

SEPTEMBER 3, 2025, NEW YORK – Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses. A deficiency in ...

March 22, 2007 — -- Metastatic cancer is cancer that has spread from the part of the body where it started (called its primary site) to other parts of the body. When cells break away from a ...